J Zahiri, M Mohammad-Noori, R Ebrahimpour, S Saadat, JH Bozorgmehr, ..

Authors
Javad Zahiri, Morteza Mohammad-Noori, Reza Ebrahimpour, Samaneh Saadat, Joseph H Bozorgmehr, Tatyana Goldberg, Ali Masoudi-Nejad
Publication date
2014/12/31
Journal
Genomics
Volume
104
Issue
6
Pages
496-503
Publisher
Academic Press
Description
Abstract Protein–protein interaction (PPI) detection is one of the central goals of functional
genomics and systems biology. Knowledge about the nature of PPIs can help fill the
widening gap between sequence information and functional annotations. Although
experimental methods have produced valuable PPI data, they also suffer from significant
limitations. Computational PPI prediction methods have attracted tremendous attentions.
Despite considerable efforts, PPI prediction is still in its infancy in complex multicellular
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